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Description
TRIUMPH-4, the first Phase 3 obesity readout (Dec 2025), reported about 28.7% mean weight loss at the top dose at 76 weeks the largest figure seen in any GLP-class trial so far
Over months of treatment, nutritional deficiencies can develop silently and only become apparent through blood work or symptoms
and 76.8% had established CVD

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The drug's mechanism of action is designed to leverage the benefits of each receptor activation