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J Leukoc Biol 92(1):5965 Zeng Z, Wang L, Ma W et al (2019) Inhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice[J]
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Genetic differences can influence appetite regulation, satiety signaling, insulin response, metabolic flexibility, and side effect sensitivity
Finally, gastrointestinal side effects such as nausea, vomiting, and diarrhea can lead to dehydration and challenged sleep, both of which contribute to exhaustion
