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doi: 10.1016/j.cell.2010.02.034

While total pharmacy spending increased from 2019 to 2024, the increase in spending on GLP-1s was greatly disproportionate to the increase in overall spending, the inspector generals office at OPM said after a look at prescription drug usage patterns of two carriers who together account for about two-thirds of FEHB enrollment

However, the full effects typically manifest over 3-6 months, with maximum weight loss usually occurring at 72 weeks (approximately 16-17 months)

Fatigue: The most common cause of fatigue during weight loss is not eating enough

Timeline and Magnitude of Rebound: What the Evidence Shows Clinical trials and real-world data provide a framework for understanding rebound patterns
