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However, it increased gastrointestinal side effects, and almost a quarter of patients experienced dysaesthesia, a painful sensation under the skin
The phase 2a liver-specific trial showed: 1 mg dose: 42.9% reduction in liver fat 4 mg dose: 57.0% reduction in liver fat 8 mg dose: 81.4% reduction in liver fat 12 mg dose: 82.4% reduction in liver fat An 82% reduction in liver fat is extraordinary
For the second experiment (Fasting study): Mice were sacrificed after 16 h of fasting, and livers were collected and snap-frozen in liquid nitrogen until further processing
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(Primary source for heart rate data) Ilkiw JL, Charman SA, Gao X, et al
