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A history of gallstones, gallbladder disease, pancreatitis, rapid weight loss, or a family history of gallstones should be discussed with the prescribing clinician

Methylglyoxal and insulin resistance in berberine-treated type 2 diabetic patients

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While they may cause modest increases in heart rate (typically 2-4 beats per minute) and modest decreases in blood pressure, they do not significantly raise core body temperature or substantially accelerate metabolic rate

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