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Efficacy and safety of lixisenatide once-daily versus exenatide twice-daily in patients with type 2 diabetes insufficiently controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X) // Diabetes Care

Secher A, Jelsing J, Baquero AF, Hecksher-Srensen J, Cowley MA, Dalbge LS, et al

The overexpression of PFKFB3 has been found not only in cultured lung fibroblasts stimulated by inflammatory cytokines [35, 45, 50], but also in myofibroblasts from IPF patients [12] and in lung tissues from different animal models of pulmonary fibrosis [12, 50]

Some patients benefit from concurrent therapy or counseling if baseline anxiety or depression exists

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