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Clinical research confirmed that the use of DPP-IV inhibitors or GLP-1 receptor agonists significantly reduced fasting and postprandial blood glucose, HbA1c, and -cell function

MALDI mass spectrometry 1 l of fragments collected from RP-HPLC was sported onto an 800 m Anchor Chip target plate (Bruker Daltonics, Bremen, Germany) separately and air dried

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The integral ER protein VAPB acts as a primary structural tether, recruiting endosomal GLP-1Rs to the MERCS upon agonist stimulation ( Figure 2 )