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In study after study, injected GLP-1 weight loss medications appear to work better on average for women than they do for men

Tirzepatide was found to improve insulin sensitivity and insulin secretory responses to a greater extent than semaglutide, and this was associated with lower prandial insulin and glucagon concentrations

Oral semaglutide 50 mg has a small benefit (additional 12% total weight reduction) over the maximum dose of the Wegovy pill which is 25 mg but with higher GI AE rates and double the cost.
