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For instance, exendin-4 has been shown to ameliorate the high glucose-induced fibronectin (FN) and type I collagen (Col1) expression in tubular epithelial cells by inhibiting the secretion of miR-192, an microRNA (miRNA) that is regulated by p53 and plays a role in renal fibrosis (Li et al., 2018)

GLP-1 medications can be incredibly effective tools, but they work best when paired with habits that support long-term health, not just short-term weight loss
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[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Titchenell P.M., Lazar M.A., Birnbaum M.J
