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Incretin-based medications and investigational drugs like Retatrutide are commonly associated with gastrointestinal side effects such as nausea, vomiting, diarrhea, constipation, and reduced appetite

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Treatment for BED largely targets the behavioral, psychological, and physical outcomes related to the disorder

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Yet, their ultimate impact will be shaped not only by biological efficacy, but also by the evolving societal and professional discourse surrounding obesity, the medicalization of weight, and the persistent challenge of stigma