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Both medications should be taken in conjunction with diet and regular exercise

Before IPTW, SGLT2i group had a greater proportion of male patients than GLP1-RA groups
While this is central to their effectiveness, it can also disrupt normal bowel habits
Those factors could independently reduce substance use disorder risk, separate from any drug effect

Researchers comparing tirzepatide dosage in units protocols should note that formulation differences do not typically require dose adjustments
