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Description
Overall, the efficacy of semaglutide in weight reduction was demonstrated in patients both with concomitant T2Dspecifically in STEP 2 [39], which included only patients with T2D, as well as in STEP 6, 7, and 10, which included both patients with and without T2D [4143]and without diabetes (STEP 1, 3, 4, 5, 8, and 9) [13, 38, 40, 4446]

Summary: GLP-1 receptor agonists are not proven to directly treat acne, though weight loss and improved insulin sensitivity from these medications may indirectly benefit some patients through hormonal changes

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NDA submission expected Q4 2026, FDA review through 2027, earliest commercial launch Q1Q2 2028

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