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30 In adolescents with obesity, semaglutide 2.4 mg once weekly led to weight loss similar to that observed in adults (a 16.1% mean reduction in BMI from baseline vs 0.6% with placebo at 68 weeks), along with improvements in cardiometabolic risk factors such as waist circumference, glycated haemoglobin (HbA 1c ), LDL-cholesterol, triglyceride and alanine transaminase levels

Clinical Evidence: Real Weight Loss Numbers from Trials The STEP trials, which tested semaglutide in adults with overweight or obesity, showed participants lost an average of 15% of body weight over 68 weeksroughly 35 pounds for someone weighing 230 pounds

Tirzepatide, dulaglutide, and cardiovascular outcomes in high cardiovascular risk patients with type 2 diabetes

But if youve built sustainable habits, such as: Eating balanced meals Controlling portion sizes Managing stress and sleep Staying active Addressing emotional eating Then youre far more likely to maintain the progress even after tapering off the medication

This is a common pattern: changes in weight and appetite control often occur weeks before you can see visible abdominal slimming