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[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Marx N, Federici M, Schutt K, Muller-Wieland D, Ajjan RA, Antunes MJ, et al

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The efficacy of RYBELSUS was not impacted by baseline age, sex, race, ethnicity, BMI, body weight, duration of diabetes and degree of renal impairment

10.1016/j.isci.2023.106057 Summary Keywords drug mechanism, metformin, type 2 diabetes, gastrointestinal tract, gut microbiota Citation Cheng M, Ren L, Jia X, Wang J and Cong B (2024) Understanding the action mechanisms of metformin in the gastrointestinal tract

This was reflected by a large reduction in their PHQ-9 score of 17 points and accompanied by significant improvements in physical health: P2 lost over 11% of their body weight