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These may include empty glass insulin vials or cartridges, insulin syringes, pen cap needles, glucose meter lancets, and insulin pump infusion sets or CGM supplies.

Our studies revealed key signaling mechanisms underlying the role of GPR17 in regulating GLP-1 secretion and suggest future opportunities for pharmacologically targeting GPR17 with inverse agonists to maximize GLP-1 secretion ![Graphical Abstract][1] Graphical Abstract ### Competing Interest Statement The authors have declared no competing interest

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