glp 1 agonist liraglutide FDA Approves Generic Version of Injection, a GLP-1 for Weight Loss Des-Gly4)-Liraglutide - GLP1 receptor agonist

Estrogen has pleotropic, beneficial effects on metabolism yet the reproductive endocrine toxicity and tumorigenic potential limits its use in chronic settings other than hormone replacement therapy

doi:10.1111/dom.12591 Suran M

Arch Neurol 39(8):46174 Yri HM et al (2012) Idiopathic intracranial hypertension is not benign: a long-term outcome study

These drugs are synthesized by means of chimeric peptide or coupled peptide, such as GLP-1/GIP, GLP-1/GIP/ Glucagon and other multi-receptor agonists

Novel studies found that GLP-1RAs such as liraglutide, semaglutide and exendin-4 reduces -synuclein aggregation respectively in MPTP (a mitochondrial complex I inhibitor) and 6-OHDA induced PD mice models as well as rat model of -synucleinopathy