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Differential effects of intracerebroventricular glucagon-like peptide-1 on feeding and energy expenditure regulation

Diabetes Care 39(10):16931701

Additionally, incretin-based therapies as a class carry a rare signal for pancreatitis , and rapid weight loss is associated with an increased risk of gallbladder disease (including gallstones)

Injecting repeatedly into the same area can, over time, lead to lipohypertrophy (hardened fatty tissue), which may reduce absorption efficiency

Common medication-related gastrointestinal symptoms usually occur shortly after injection, improve between doses, and gradually diminish with continued use