why am i not losing weight on a glp 1 GLP-1? (Even When It's Working) GLP-1 Medications Aren't the Only

Gut and Liver, 9 (4), 464469

For these reasons, beyond T2DM, liraglutide and semaglutide have also been approved for the treatment of obesity in diabetic and non-diabetic patients [16,17]

The clinical significance of this added increase in serum creatinine relative to placebo is not known

bariatric procedure volumes declined 11.4% in 2025 reversing a two-decade growth trend as semaglutide and tirzepatide provide comparable weight loss outcomes for class I and class II obesity without surgical risk, recovery time, or nutritional deficiency complications

Peptide systems previously deemed too complex, too pleiotropic, or too impractical may now be among the most promising candidates for next-generation therapeutics