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Risk of bias: all four RCTs were rated low risk by RoB2 (with some concerns for open-label outcome ascertainment in three trials, a domain-specific issue that does not alter the overall RoB2 category from low)

But this story isn't of a single breakthrough

In the world of GLP-1 everyone is talking about Retatrutide

Its notoriously hard to DIY, but its a relatively inexpensive service

GLP-1 medications like semaglutide work best as long-term weight management tools, not short-term fixes
