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Thompson also cautioned that healthcare providers and patients still lack clarity on the long-term implications of the treatments

Study Population The study included patients eligible for antiobesity medications (AOMs) between January 1, 2014, and January 31, 2024

The emergence of clinically effective dual and triple agonists holds promise for enhanced metabolic outcomes, although the precise mechanisms of drug actions remain to be fully elucidated

We explored these limitations with meta-regression, as well as with subgroup analysis, and the results were unchanged

This is confirmed by the impaired glucose-stimulated release of GLP-1 in mice lacking either T1R3 or -gustducin (244)