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2021;11:e2259

Some patients report feeling colder than usual whilst taking these medications, although this is not listed as an adverse effect in the Summary of Product Characteristics (SmPCs) for GLP-1 preparations in the UK

This article does not provide specific storage temperatures, in-use shelf lives, or handling instructions for retatrutide powder, as no product-specific, MHRA-approved guidance is publicly available and any such advice outside the sponsor's documentation would be speculative and potentially unsafe

Swallow the tablet whole with up to half a glass (approximately 120 mL) of plain water
