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Description
Rates of major abdominal surgery were similar between groups, with no signal of increased surgical risk
Preservation must therefore be intentional

The aim of this analysis was to compare the efficacy of tirzepatide 5, 10 and 15 mg with semaglutide 2 mg using an adjusted indirect treatment comparison (aITC) based on results from the SURPASS2 2 and SUSTAIN FORTE 10 trials
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They may support blood sugar balance

315317 GLP-1R is expressed in human monocyte-derived macrophages and the mouse macrophage cell line RAW264.7
