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Across four phase 2 and five phase 3 clinical trials, 1.6% of patients developed anti-drug antibodies to dulaglutide, but the effect of antibodies on efficacy is unclear
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[DOI] [PubMed] [Google Scholar] 105.Calanna S., Christensen M., Holst J.J., Laferrre B., Gluud L.L., Vilsbll T., Knop F.K

As a result semaglutide was discontinued, and the patient was referred to a psychiatrist who treated her for obsessive compulsive disorder with high dose fluoxetine 60 mg daily and psychotherapy
