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What were GLP-1s designed to do, and who are they for

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Clinical Endocrinology & Metabolism 21, no

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demonstrated that GLP1-R activation leads to a modest but statistically significant increase in cAMP concentration in mixed leucocyte populations, including Tregs (32)

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And the ATTAIN-MAINTAIN trial in Nature Medicine showed patients can switch from injection to a daily pill and keep 75-80% of their weight loss

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