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Exendin-4, like other GLP-1RAs, requires frequent administration due to its short plasma half-life

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Patients should be educated on proper technique, including allowing the medication to reach room temperature before injection and following the specific instructions for their device as detailed in the manufacturer's Instructions for Use (IFU)

The loss of lean body mass, or muscle, occurs as a normal result of substantial weight loss in people who have excess body fat and who live sedentary lives, Quebbemann says