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These medications have undergone extensive clinical trials to evaluate their efficacy and safety in managing type 2 diabetes and, more recently, their potential for weight loss

2025 Oct 16;9:25424823251388650

Although genetic factors may play a role in the etiology of DM2 [2], there is now convincing evidence that DM2 is strongly associated with modifiable factors, such as diet
270,271 Additionally, slower gastric emptying helps stabilize postprandial blood glucose levels
(eClinicalMedicine, 2024), a randomized, double-blinded, two-centre, phase 2 trial of once-weekly semaglutide 1.0 mg versus placebo in 64 adults with increased fracture risk
