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Prospective trials with standardized vestibular examinations would offer a complete definition of GLP-1RA effects on vestibular function, ideally involving objective vestibular testing, patient-reported outcome measures, and prolonged follow-up periods

Adherence to the titration schedule strongly predicts outcomes

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Furthermore, exendin-4 administration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in vivo animal model of PD has been shown to inhibit microglial activation thereby minimizing the loss of dopaminergic neurons in the pars compacta of the substantia nigra and the striatum [78]