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Single-chain variable fragment albumin fusions bind the neonatal Fc receptor (FcRn) in a species-dependent manner: implications for in vivo half-life evaluation of albumin fusion therapeutics

There are currently four GLP-1 receptor agonists approved for use in United States and five approved for use in the European Union (Table 1): exenatide twice daily, liraglutide once daily, exenatide once weekly, albiglutide once weekly, and lixisenatide once daily (available in Europe)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 292.Keenan S.J., Cooke M.B., Hassan E.B., Chen W.S., Sullivan J., Wu S.X., El-Ansary D., Imani M., Belski R