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"There is the perception that these are miracle drugs that work for everybody," she says

After weighting the cohorts for inverse probability of treatment, the researchers found that, compared with second-line GLDs, ADRD risk was significantly lower with both GLP-1 receptor agonists (adjusted HR = 0.67

Whilst GLP-1 receptor agonists slow the digestive process, there is no substantial evidence that they significantly impair nutrient absorption in individuals with normal pancreatic function

Decision Framework: Questions to Ask Any Provider Rather than identifying a "best" option, individuals considering semaglutide treatment should evaluate their circumstances using these questions: Medical Appropriateness Do I have any contraindications listed in prescribing information

Results Interim analysis The trial was halted early in October 2023 after the DSMB performed an interim analysis after 570 events had accrued, and stopping rules were met