glp 1 receptor agonists beyond their pancreatic effects Glucagon-like peptide-1 receptor: mechanisms and advances in therapy GLP1 Receptor Agonists—Effects beyond Obesity
Description
The Association Between Obesity and the 5-Year Prevalence of Morbidity and Mortality Among Adults With Type 2 Diabetes

There is a risk of weight regain if the medication is discontinued

Injected semaglutide binds to these GLP-1 receptors and reduces appetite for nearly a week, ultimately causing people to eat less and lose weight
Most of them were not on nephroprotective drugs such as SGLT-2 inhibitors (75%) and mineralocorticoid receptor antagonists (92%), while 81% of patients were on ACE-I or ARBs [49]

What has become clearer is just how widely GLP-1 signaling is distributed throughout the brain
