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In Victoza clinical trials, severe gastrointestinal adverse reactions were reported more frequently among patients receiving Victoza (1.2 mg 4.4 %, 1.8 mg 4.2 %) than placebo (1.1 %)
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Treatment duration was estimated using prescription span, and adherence could not be confirmed

To improve outcome observability, we restricted the analysis to patients receiving usual care within a Truveta health care system in the prior year, defined as an interaction in both consecutive 6-month periods in the year before GLP-1 RA initiation
161,167 Small molecule GLP-1RAs Currently, most GLP-1RAs are based on proteins or peptides, meaning they are large molecules typically administered via injection