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These changes occur whether or not you used medicationthey are hardwired survival responses

doi:10.1210/jc.2015-1176 Hansen MS, Wlfel EM, Jeromdesella S, et al

Compared to age-matched controls, insulin resistance in the brains of PD patients is independent of peripheral insulin resistance and manifests as severe abnormalities in brain insulin signal transduction

GLP-1 medications carry risks including gastrointestinal symptoms, pancreatitis, and gallbladder disease, requiring specialist supervision

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