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GLP-1 medications cause systemic fat reduction rather than targeted loss, meaning skin looseness can occur throughout the body rather than in isolated areas

The lyophilised (freeze-dried) format supplied for research supports stability during storage and transport, which is particularly relevant across Australia's varied climate

We assessed the risk of a composite kidney outcome, including confirmed 40% eGFR loss or end-stage kidney disease, and the risk of new macroalbuminuria

The second person will regain weight faster when they stop the medication because their body now burns fewer calories at rest

However, in the covariate analysis of this study, no significant effects of baseline weight, baseline BMI, or proportion of males on the weight-reducing impact of GLP-1RA drugs were found