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Antidepressants and anticholinergics Anticholinergic medications, including many antidepressants, antihistamines, and bladder medications, cause dry mouth by directly blocking the nerve signals that stimulate saliva production

Evidence most strongly supports continuous therapy as the most reliable long-term approach

It is important to distinguish between a simple medication depot and more serious complications such as lipohypertrophy (fatty lumps from repeated injections in the same site) or injection site abscesses

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Bottom line: GLP-1 patches may contain recognisable ingredients, but there is currently no strong evidence that those ingredients are absorbed through the skin in amounts sufficient to support the effects claimed