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Description

Musculoskeletal factors unrelated to medication: Type 2 diabetes itself is associated with increased prevalence of musculoskeletal conditions, including back pain, due to factors such as diabetic neuropathy, reduced physical activity, obesity, and inflammatory processes

A 2023 retrospective cohort analysis in JAMA Internal Medicine (N=16,922) found that patients on a GLP-1 RA plus an opioid had a 33% higher rate of bowel obstruction-related ED visits compared to patients on a GLP-1 RA alone [5]

For this, we target intracellular and membrane-bound proteins implicated in inflammatory pathways of AD

Medications such as semaglutide, liraglutide, and tirzepatide work by mimicking the natural GLP-1 hormone, which helps regulate blood sugar and control appetite