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The physiological relevance of this concentration-dependent signaling complexity has been demonstrated in human adipocytes, where picomolar GLP-1 promoted lipogenesis while nanomolar GLP-1 induced lipolysis

A Cleveland Clinic analysis of nearly 8,000 patients found that discontinuing semaglutide and tirzepatide did not lead to significant immediate weight regain in clinical practice

How Serena Williams admission of using a GLP-1 drug could impact the stigma of obesity Serena Williams GLP-1 disclosure may shift obesity conversations, though treatment requires a holistic approach, Northeastern experts say

5 Myths Debunked." Intermountain Health: "Your friendly guide to GLP-1 weight loss: what works, what doesn't and what's next." Cleveland Clinic: "GLP-1 Agonists," "Body Mass Index (BMI)."