glp-1 vs metformin Comparing Glucagon‐like peptide‐1 receptor agonists versus in drug‐naive patients: A nationwide cohort study - Sørensen - 2024 - Journal of Diabetes Diagram summarizing how metformin, gliclazide,
Description
The difference is hours, not days, so it primarily affects the acute post-injection experience rather than overall weekly efficacy
Its underexploitation in metabolic indications likely reflects disciplinary silos rather than a lack of biological relevance

Friendly reminder of refill times

[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Saeedi P., Petersohn I., Salpea P., Malanda B., Karuranga S., Unwin N., Colagiuri S., Guariguata L., Motala A.A., Ogurtsova K., et al

Whilst there is consensus appreciation of the reduction in perioperative cardiometabolic complications these agents provide in improving glycaemic control, it would be remiss to discount the unquantified risk of aspiration from GLP-1 agonists during airway management
