glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]
Description
You still enjoy eating, but it doesnt drive behavior in the same way. That mechanism has sparked interest far beyond obesity research
![glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]](https://tmedweb.tulane.edu/pharmwiki/lib/exe/fetch.php/glp1.png?w=600&tok=baf39c)
This is where retatrutide has been shown to cause weight loss of up to 24.2% after 48 weeks
![glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]](https://ars.els-cdn.com/content/image/1-s2.0-S0163725809001168-gr4.jpg)
Bueter, M
![glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]](https://www.invivogen.com/sites/default/files/styles/wide/public/invivogen/media/image/incretin%20ligands%20landing%20page%20invivogen.png?itok=oC4_H43g)
Increasing healthcare expenditures of governments and availability of low-cost generic drugs are supporting the widespread use of incretin mimetics in disease treatment
![glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]](https://cdn.lecturio.com/assets/Nursing_CS_Injectable_Non-Insulin_Medication_Management_of_Diabetes-02.jpg)
However, pemvidutide showed a NASH reduction signal (reduction in liver fat) in an earlier Phase 1b trial interim analysis
![glp 1 receptor agonists incretin mimetics Incretins: How we got here, where we're at and what is coming next glp-1_analogs [TUSOM | Pharmwiki]](https://www.thelancet.com/cms/10.1016/S0140-6736(06)69705-5/asset/079012c9-a24f-4391-ba39-2f5d03668f6f/main.assets/gr1_lrg.jpg)