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Have certain medical contraindications: GLP-1 medications should not be used by individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
The potential side effects of GLP-1 drugs are no fun: nausea, vomiting, fatigue, diarrhea, constipation
His legal filings suggest that he believes that taking Trulicity caused or contributed to these health problems
For twice-daily formulations like immediate-release exenatide (Byetta), timing is more prescriptive
Figure 1 provides an example of an LBA method developed on the MSD platform for quantifying exenatide in human plasma
