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This activation triggers several physiological responses that can contribute to weight loss: Appetite regulation: Semaglutide helps reduce appetite and increase feelings of fullness (satiety)

( 10.1056/NEJMoa2206038) [DOI] [PubMed] [Google Scholar] Jastreboff AM, Kaplan LM, Frias JP, Wu Q, Du Y, Gurbuz S, Coskun T, Haupt A, Milicevic Z, Hartman ML, et al

performed single-cell RNA sequencing of the NG neurons, morphological characterization, and behavioural analysis in mice to generate a map of the NG neurons that innervate the stomach and intestine 7