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Apr 2016;4(4):306-22

By week 812, energy levels normalize for the majority of users, though some individuals experience mild lingering tiredness into month three
The patents for Semaglutide are ending soon in India, Canada, and Brazil

Introduced by Novo Nordisk in early 2026, oral semaglutide marked a breakthrough as the first oral GLP-1 medication specifically approved for weight loss

The drugmaker didn't immediately respond to a request for comment, but in a February interview with NPR, Eli Lilly CEO David Ricks said offering a discount for patients taking the higher doses who reorder every 45 days is an "opportunity for us to reward people who go with the program and stay on the medication." Some people are talking online about buying the active ingredient from China and mixing the obesity drugs in their homes
