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Description
This Comment highlights emerging evidence and advocates for clinical strategies that prioritize muscle preservation to ensure the long-term success and safety of pharmacological weight management.

For GLP-1 agonist therapy, start with the lowest dose and gradually titrate up to minimize gastrointestinal side effects, following specific dose escalation ...

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Ania Jastreboff at #ADA2026 TRIUMPH-1: Phase 3 Obesity Trial with Retatrutide Retatrutide , a once-weekly triple hormone receptor agonist
