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I would first obtain a detailed patient history, blood work, echocardiogram, and medication reconciliation to identify more common causes of palpitations/arrhythmias. Additionally, making some lifestyle changes may be helpful in this situation

The anticipation is worse than the reality

The trial did not measure fat-versus-lean composition of the weight gained back in the five-milligram group or the placebo group

In the STEP-1 study, patients treated with semaglutide lost nearly 14 kg in total, with 8.5 kg (60%) being fat loss and 5 kg (38%) being lean mass loss, which exceeds normal physiological expectations

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