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Medical writing support, under the direction of the authors, was provided by Eric Comeau, Ph.D., of CMC Connect, McCann Health Medical Communications and was funded by Pfizer Inc., New York, NY, USA, in accordance with Good Publication Practice (GPP3) guidelines (Ann Intern Med 2015;163:461464).

This transition is essential because these conditions share overlapping symptoms yet exhibit distinct endocrine and reward-related profiles that may influence treatment response and guide clinical decision-making

This means oral medications may be absorbed more slowly or differently

I = 89.1%)

While existing medications to reduce drinking act primarily on the brain, GLP-1s appear to work partly through the gut