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Instead, they offer plant-based ingredients thought to support natural appetite signaling

doi:10.1038/s41598-017-16488-x 73

Transplanting the gut microbiota from either obese or lean mice or humans into GF mice recapitulates the host phenotype, highlighting the potential causality of the gut microbiota in the development of metabolic dysregulation 252,253

Metformin should be withheld on the day of surgery if the patient is fasting, and should not be restarted until normal renal function is confirmed, particularly after procedures using contrast agents