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Semaglutide is often optimized to maximize weight loss, yet it remains unclear whether long-term cardiovascular benefit is more closely associated with achieved weight reduction or therapeutic exposure

Looks like $LLY have, as expected, cemented their lead as the best in class drug makers and Im not sure how other pharmas are going to compete with this treatment

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The first study shows that more economical and sustainable weight loss can be maintained by inducing subjects with tirzepatide and changing to oral orforglipron for the long term