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Description
Gradual escalation allows the body to adjust to GLP-1 receptor activation while maintaining tolerability

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26 Another study also found a statistically significant decrease in the development of glaucoma, with a duration-response pattern: Individuals using GLP-1RAs for 3 or more years had a higher risk reduction of 29%

Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, or severe pancreatitis

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