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In clinical trials, GLP1, the actibe ingredient in the brand name medication Wegovy, has been found to lead to significant weight loss compared to placebo, as well as improve several metabolic markers such []
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Treatment with GLP1RAs resulted in unaffected or reduced Cmax and delayed tmax of drugs with high solubility and permeability (warfarin, contraceptive pills, acetaminophen), drugs with high solubility and low permeability (angiotensin converting enzyme inhibitors), drugs with low solubility and high permeability (statins) and drugs with low solubility and permeability (digoxin)
However, cardiovascular disease remains the primary cause of mortality in this population
