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For those whose weight challenges are linked to insulin resistance or hormone imbalance, inositol may offer a more targeted approach

Qsymia (Phentermine-topiramate): This is often considered the most effective oral pill

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In part, these medications work by sending signals to the brain to decrease appetite and by slowing digestion, which helps people feel fuller for longer

For those using GLP-1 medications for weight management, reduced efficacy may manifest as weight loss plateau or regain