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Clinical trial data show the following side effects related to heartburn: Gastroesophageal reflux disease: 5% of Wegovy users, 3% of the placebo group

The CORT-X trial will examine if mitigation of stress-mediated pathogenesis of AD is a possible target for intervention in individuals at risk for this disease (NCT04601038)

Parallel investigation of regulatory mechanisms revealed significant involvement of epigenetic pathways, including targets of the PRC2 (P adj -value = 0.0078) and genomic regions overlapping breast cancer amplicons (17q21/q25

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